the initial dose is 12,5 mg once a day in the first 2 days of therapy, then 25 mg once a day. If necessary, in the future, the dose can be increased at intervals of at least 2 weeks, bringing to the maximum recommended dose of 50 mg once a day (or divided into 2 doses)
Coronary artery disease
the initial dose is 12,5 mg 2 times a day for the first 2 days, then 25 mg 2 times a day. If necessary, subsequently, insufficiency, the dose can be increased at intervals of at least 2 weeks, bringing to a maximum daily dose of 100 mg, divided into 2 doses
Chronic heart failure
the dose is selected individually, careful monitoring by a doctor is necessary, the recommended initial dose is 3.125 mg (1/2 tablet of 6.25 mg) 2 times a day for 2 weeks
In elderly patients, data on the need for dose adjustment are not available.
There are contraindications, consult with a specialist before use