Severe acute or chronic pain with injuries and postoperative pain, with colic, with cancer and other conditions where other therapeutic measures are contraindicated.
Fever resistant to other treatments.
The dose depends on the severity of pain or fever, as well as individual susceptibility to the action of analgesics.
The tablets should be swallowed whole with a sufficient amount of liquid. Initially, the lowest effective dose should be used.
The maximum effect of the drug develops, usually after 30-60 minutes. after ingestion.
For adults and adolescents over 15 years old (with body weight> 53 kg)
is 500-1000 mg (1-2 tablets). With insufficient effect, a single dose can be taken up to 4 times a day. The maximum daily dose is 4000 mg (8 tablets). Duration of admission is not more than 5 days as an anesthetic and not more than 3 days as an antipyreticо
elderly patients need to reduce the dose, since they may have reduced excretion of metamizole sodium metabolites
Severe general condition and impaired creatinine clearance
in patients with severe general condition and creatinine clearance impairment, it is necessary to reduce the dose, since their excretion of metamizole sodium metabolites may be reduced
Renal or hepatic impairment
since in patients with impaired renal or hepatic function, the rate of elimination of the drug is reduced, multiple doses of high doses should be avoided. With short-term use, dose reduction is not required. No long-term experience
There are contraindications, consult with a specialist before use